Wednesday, April 20, 2011

Cardiovascular diseases

The current post genomic era has 
characterized by a large increase in 
the number of potential therapeutic targets amenable to investigation.Insilico structure based design is rapidly becoming the lead identification corner stone of many drug discovery processes.design of drugs is an iterative process,which begins by the identification of a compound.traditional approaches to drug discovery rely on a step-wise synthesis & screening program for large numbers of compounds to optimize activity profiles.the methods are based on the interaction theory between drugs &their target proteins.cardiovascular diseases refer the class of diseases that involve the heart or blood vessels(arteries and veins).types of cardiovascular diseases include:arrythmias,hypertension,myocardial infraction,cardiomyopathy etc. Cardiomyopathy,which literally means "heart muscle disease",is the deterioration of the function of the myocardium(i.e.,the actual heart muscle)for any reason.People with cardiomyopathy are often at risk of arrhythmia or sudden cardiac death or both.